CRISP-R/Cas9 Mediated Deletion of Copper Transport Genes CTR1 and DMT1 in NSCLC Cell Line H1299. Biological and Pharmacological Consequences

Copper, the highly toxic micronutrient, plays two essential roles: it is a catalytic and structural cofactor for Cu-dependent enzymes, and it acts as a secondary messenger.In the cells, copper is imported by CTR1 (high-affinity copper transporter 1), a transmembrane high-affinity copper importer, and DMT1 (divalent metal transporter).In cytosol, en

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An analytical study of the publications issued by the LPD section of IFLA and its role in enhancing the quality of library and information services for people with visual disabilities.

This study aims to reveal the contribution of the International Federation _IFLA_ in enhancing the quality of library and information services for people with visual disabilities through publications issued by the LPD section.We have adopted a content analysis approach and have followed Desk many steps, one of the importants, from the inventory of

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Creating a Pharmacy Internship: A Toolbox for Success

Objective: To describe available compensated student internships and provide guidance for Vehicle Toys new program development.Methods: A search was conducted using PubMed, MEDLINE, and Google with the following search terms: pharmacy, intern, internship, and student.All English language publications were considered for inclusion.Articles describin

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Uncommon Dorsal Radiocarpal Fracture Dislocation Complicated With Median Nerve Palsy: Case Report, Review of the Literature, and a New Classification System Guiding the Management

We report the case of a 36-year-old lorry driver who sustained left dorsal radiocarpal FRESH MINT FOAMING HAND SOAP fracture dislocation and left median nerve injury in a traffic accident in 2010.Emergency operation of closed reduction, cross-wrist-bridging external fixation, percutaneous transradial styloid Kirschner wire fixation, decompression o

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